You are currently browsing the category archive for the ‘Science’ category.

If you think that arguments based in truth, eventually you will run up against people who are so deep into the gender-cult that they have no idea what is real and what is dogma.

 

Be careful though, your audience will often defend their dogmatic views by any means necessary: Name calling, threats, and excommunication from the arena.

 

Tread with care and realize that you need to love the truth more than the shallow “acceptance” of others.

 

No so gentle reminder of the reality of the situation.

The full text of the Health and Human Services Systematic review can be found here.

Introduction

In our final post, we explore the systematic review’s findings on psychotherapy as an alternative to medical interventions for pediatric gender dysphoria, alongside international shifts in treatment approaches. The Department of Health and Human Services’ 2025 report (Chapter 14, pages 239-259) highlights the potential of non-invasive psychotherapy and the growing global retreat from medicalized care.

Key Findings on Psychotherapy and Global Trends

The review notes a significant gap in research on psychotherapeutic approaches for gender dysphoria, partly due to the mischaracterization of such treatments as “conversion therapy” (page 252). However, psychotherapy is a well-established, non-invasive method for managing mental health conditions, including those often co-occurring with gender dysphoria, like depression and anxiety (page 248). Systematic reviews have found no evidence of harm from psychotherapy in this context, unlike medical interventions, which carry significant risks (page 16).

Internationally, countries like Finland, Sweden, and the UK have shifted away from the “gender-affirming” model, prioritizing psychosocial interventions (pages 142-145). The UK’s Cass Review, for instance, found weak evidence for medical interventions and recommended psychotherapy as a first-line approach (page 63). These countries have restricted puberty blockers and hormones due to concerns about their safety and efficacy, reflecting a broader recognition of the need for caution (page 56).

Looking Forward

The rise in youth gender dysphoria coincides with a broader mental health crisis among adolescents, suggesting that social and psychological factors may play a significant role (page 239). Psychotherapy offers a way to address these underlying issues without the irreversible risks of medical interventions. As more countries adopt this approach, the U.S. faces pressure to align its practices with emerging evidence.

Three Arguments Against Transitioning Children

  1. Psychotherapy as a Safer Alternative: Psychotherapy is a non-invasive option with no reported adverse effects in treating gender dysphoria, unlike medical interventions that risk serious harm (page 16).

  2. International Restrictions Highlight Risks: Countries like the UK and Sweden have restricted medical interventions due to weak evidence and significant risks, suggesting a need for caution in the U.S. (page 56).

  3. High Rates of Natural Resolution: The natural history of gender dysphoria shows that it often resolves without medical intervention, supporting the use of psychotherapy to explore identity without irreversible steps (page 21).

References

  • Department of Health and Human Services. (2025). Treatment for Pediatric Gender Dysphoria: Review of Evidence and Best Practices, page 16.

  • Ibid., page 56.

  • Ibid., page 21.

  Find the full HSS Systematic Review here.

Introduction

In our second post, we dive deeper into the risks associated with medical treatments for pediatric gender dysphoria, as outlined in the Department of Health and Human Services’ 2025 review. While proponents of “gender-affirming care” argue these interventions are essential, the systematic review (Chapter 7, pages 106-124) highlights significant physiological and psychological risks that deserve careful consideration.

Key Findings on Risks

The review details how puberty blockers, cross-sex hormones, and surgeries impact young bodies. Puberty blockers, used to halt natural pubertal development, can lead to impaired bone mineral density, increasing the risk of fractures later in life (page 110). They may also affect neurocognitive development and sexual function, with potential long-term consequences that are not fully understood (pages 111-112). Cross-sex hormones, such as testosterone for girls or estrogen for boys, introduce risks like cardiovascular disease, metabolic disorders, and infertility (pages 118-119). Surgeries, though less common, carry risks of complications and regret, particularly when performed after early pubertal suppression (page 120).

The review emphasizes that these risks are not hypothetical—they are grounded in established physiological knowledge. For instance, blocking puberty disrupts normal developmental processes critical for bone, brain, and reproductive health (pages 108-112). Yet, the evidence for these interventions’ benefits remains weak, with systematic reviews unable to confirm improvements in mental health or quality of life (page 13).

Why This Matters

Children and adolescents are particularly vulnerable to these risks because their bodies are still developing. The irreversible nature of many of these effects—like sterility or surgical changes—raises ethical concerns about applying them to minors who may not fully grasp the long-term implications. The review’s findings align with international trends, such as restrictions in Finland and Sweden, where psychotherapy is now prioritized (pages 142-143).

Three Arguments Against Transitioning Children

  1. Irreversible Physical Harms: Puberty blockers and hormones can cause permanent effects like infertility, reduced bone density, and sexual dysfunction, which are particularly concerning for developing children (page 14).

  2. Uncertain Long-Term Outcomes: The review found no reliable evidence that medical interventions improve long-term mental health or quality of life, making the risk-benefit ratio unfavorable (page 13).

  3. Ethical Concerns with Consent: Adolescents may lack the maturity to consent to treatments with lifelong consequences, especially given the uncertain benefits and significant risks (page 155).

References

  • Department of Health and Human Services. (2025). Treatment for Pediatric Gender Dysphoria: Review of Evidence and Best Practices, page 14.

  • Ibid., page 13.

  • Ibid., page 155.

  The text of the full report can be found here.

Introduction

The treatment of gender dysphoria in children and adolescents has become a highly debated topic. A recent report from the Department of Health and Human Services (May 1, 2025) provides a comprehensive review of the evidence behind these treatments. This first post in our series explores the overall findings of the systematic review, highlighting the quality and limitations of the evidence for medical interventions like puberty blockers, cross-sex hormones, and surgeries.

Key Findings from the Systematic Review

The report’s “umbrella review” (Chapter 5, pages 77-96) evaluated existing systematic reviews to assess the benefits and harms of treatments for pediatric gender dysphoria. The findings are striking: the evidence supporting these interventions is of very low quality. This means that claims about their benefits—such as improved mental health or quality of life—are uncertain and may differ significantly from the true effects. Studies often lack rigorous methodology, with issues like small sample sizes, short follow-up periods, and potential publication bias (page 103) clouding the results.

For example, the review found that studies claiming benefits from puberty blockers or hormones, such as de Vries et al. (2011, 2014) and Tordoff et al. (2022), are short-term and observational, lacking the robustness of randomized controlled trials (pages 98-101). These studies often fail to account for confounding factors like concurrent mental health treatment, making it hard to attribute outcomes solely to medical interventions. Additionally, the review notes a lack of systematic tracking of harms, which may underreport risks like infertility or bone density issues (page 13).

What This Means

The low-quality evidence raises serious questions about the widespread use of medical interventions for children with gender dysphoria. Without clear data on long-term outcomes, families and clinicians face uncertainty when making decisions. This gap in evidence has led countries like the UK to restrict puberty blockers, prioritizing psychosocial approaches instead (page 13).

Three Arguments Against Transitioning Children

  1. Insufficient Evidence of Benefit: The systematic review found that the evidence for psychological benefits from puberty blockers, hormones, or surgeries is very low quality, with studies often biased or inconclusive (page 13). This uncertainty makes it risky to pursue invasive treatments with unproven efficacy.

  2. Significant Risks of Harm: Medical interventions carry serious risks, including infertility, sexual dysfunction, impaired bone density, and potential cognitive impacts (page 14). These risks are particularly concerning for children, whose bodies and minds are still developing.

  3. Natural Resolution of Gender Dysphoria: Research suggests that gender dysphoria often resolves without intervention in many cases, especially when untreated (page 21). Medical transition may disrupt this natural process, leading to irreversible changes for children who might otherwise reconcile with their bodies.

References

  • Department of Health and Human Services. (2025). Treatment for Pediatric Gender Dysphoria: Review of Evidence and Best Practices, page 13.

  • Ibid., page 14.

  • Ibid., page 21.

Read the full text at the APA and think to yourself, when did the APA lose it’s mind?

 

Let’s breakdown the claims and look at the evidence.  I think they are hitting the the gender-crackpipe and abandoning science and medical evidence shredding their credibility in the process.

### Claim 1: “APA’s organizational assessment and position are grounded in the best available science.”
**Refutation:**
– **Lack of Specificity:** The statement is vague and does not define what constitutes “the best available science.” Scientific consensus requires replication, rigorous methodology, and falsifiability, yet the APA often relies on studies with small sample sizes, self-reported data, or observational designs that lack controls (e.g., many transgender health studies cited later). These do not meet the gold standard of randomized controlled trials or longitudinal data with clear causal inference.
– **Ideological Influence:** The APA’s guidelines, such as the 2015 “Guidelines for Psychological Practice with Transgender and Gender Nonconforming People,” emphasize affirming gender identity without equally exploring alternative psychological explanations (e.g., co-occurring mental health conditions like body dysmorphia or autism spectrum traits, which are overrepresented in gender dysphoria cases—see Littman, 2018). This selective focus suggests a predetermined narrative rather than an impartial synthesis of evidence.
– **Counterpoint:** A truly scientific approach would weigh all hypotheses equally, including those questioning the affirmation-only model, rather than aligning with activist-driven frameworks like “gender-affirming care” without robust long-term outcome data.

### Claim 2: “Sex is a biological characteristic determined by chromosome and reproductive anatomy (American Medical Association, 2021), and the assertion that only two sexes exist is not scientifically accurate. Approximately 1.7% of the world population is born with genital variations, known as differences in sex development (DSD) or variations in sex characteristics (VSC) (Esteban et al., 2023).”
**Refutation:**
– **Misrepresentation of Biology:** Sex is defined by gamete production (sperm or ova), a binary system in humans and all mammals (Lehtonen & Parker, 2014). Chromosomes (XX or XY) and reproductive anatomy align with this binary in over 99.98% of cases, per rigorous estimates (Sax, 2002). DSDs (e.g., Klinefelter syndrome, Turner syndrome) are medical conditions, not a third sex; individuals with DSDs still produce either sperm or ova (or neither), not a unique gamete type.
– **Inflated Statistics:** The 1.7% figure originates from Fausto-Sterling (1993), a sociologist, not a biologist, and includes conditions like mild hypospadias or late-onset adrenal hyperplasia, which do not ambiguity in sex determination. More accurate estimates from clinical data (e.g., Blackless et al., 2000, revised by Sax, 2002) place true DSD prevalence at 0.05% to 0.1%, a tiny fraction. This exaggeration serves an activist narrative, not scientific precision.
– **Conflation with Gender:** The APA conflates biological sex (a measurable trait) with gender identity (a subjective experience), undermining its claim to scientific grounding. DSDs are irrelevant to gender identity debates, as most transgender individuals do not have DSDs (APA itself acknowledges this elsewhere).

### Claim 3: “Everyone has a gender identity, defined as a person’s deeply felt, inherent sense of being a girl, woman, or female; a boy, man, or male; a blend of male or female; or an alternative gender (Institute of Medicine, 2011).”
**Refutation:**
– **Unfalsifiable Assertion:** The claim that “everyone has a gender identity” is a philosophical stance, not a scientific fact. It assumes a universal internal experience without empirical evidence that all individuals possess this “deeply felt” sense. Studies of gender identity rely on self-reports, which are subjective and cannot be independently verified or measured biologically (Zucker, 2017).
– **Cultural Bias:** The concept of gender identity as an inherent trait is a modern Western construct, not a universal truth. Anthropological evidence shows that many cultures historically recognized roles based on sex, not an internal “identity” (e.g., Nanda, 1990, on hijras in India). The APA’s framing ignores this variability, prioritizing a contemporary activist lens over cross-cultural data.
– **Lack of Evidence:** No biological marker (e.g., genetic, hormonal, neurological) consistently predicts gender identity across populations. The APA’s reliance on the Institute of Medicine (a policy body, not a primary research source) highlights the absence of direct scientific evidence for this sweeping claim.

### Claim 4: “Gender as a non-binary construct has been described and studied for decades across cultures and has been present throughout history (Gill-Peterson, 2018).”
**Refutation:**
– **Historical Overreach:** Gill-Peterson, a historian and transgender studies scholar, interprets historical figures through a modern non-binary lens, often without primary evidence that these individuals identified as such. For example, “third gender” roles (e.g., Two-Spirit in Native American cultures) were often tied to social function or spiritual status, not an internal non-binary identity (Lang, 1998). This is retrospective activism, not scientific history.
– **Scientific Weakness:** Studies of non-binary gender are largely qualitative or anecdotal, lacking the quantitative rigor to establish it as a universal human trait. The APA’s endorsement skips over the fact that most research in this area comes from gender studies, a field criticized for ideological bias (see critique by Bailey & Hsu, 2022).
– **Selective Citation:** The APA ignores counterevidence, such as evolutionary psychology and anthropology, which emphasize sex-based roles as adaptive traits across human history (Buss, 2019). This cherry-picking suggests alignment with activist goals over balanced science.

### Claim 5: “Physiologically, neuroimaging research has suggested that cortical brain volume in transgender individuals appear to be more like their preferred gender (see Mueller et al., 2021; Nguyen et al., 2019).”
**Refutation:**
– **Overstated Findings:** Mueller et al. (2021) and Nguyen et al. (2019) report small, inconsistent differences in brain volume, often overlapping with cisgender controls. These studies have small sample sizes (e.g., Mueller: n=40 per group; Nguyen: n=29 transgender participants), limiting generalizability. Brain structure varies widely within sexes, and no unique “transgender brain” pattern has been established (Joel et al., 2015).
– **Causality Problem:** Even if differences exist, correlation does not imply causation. Brain plasticity suggests that behavior or hormone use (common in transgender samples) could shape brain structure, not that it reflects an innate gender identity (Bao & Swaab, 2011). The APA ignores this alternative explanation.
– **Scientific Consensus Absent:** Larger meta-analyses (e.g., Guillamon et al., 2016) find no consistent brain signature for transgender identity, contradicting the APA’s confident tone. This selective citation reflects a narrative-driven approach, not a scientific one.

### Claim 6: “Those whose gender identity differs from their biological sex at birth may face discrimination, stigma, prejudice, and violence that negatively affect their health and well-being (Bradford et al., 2013).”
**Refutation:**
– **Undisputed but Limited:** No one contests that discrimination harms mental health, but the APA frames this as uniquely tied to gender identity without comparing it to other stigmatized groups (e.g., racial minorities, obese individuals). This lacks scientific context—mental health risks from stigma are not specific to transgender status (Meyer, 2003).
– **Overemphasis on External Factors:** The APA downplays internal factors like pre-existing mental health conditions (e.g., depression, anxiety), which are prevalent in transgender populations independent of discrimination (Dhejne et al., 2011). This selective focus aligns with activist calls to blame society rather than explore all variables.
– **Weak Citation:** Bradford et al. (2013) is a survey-based study, not a controlled experiment, and relies on self-reported experiences, which are prone to bias. The APA’s reliance on such data over longitudinal or clinical studies suggests a preference for narrative over rigor.

### Claim 7: “Research demonstrates that gender-related discrimination appears to be the most documented risk factor for poor mental health among transgender individuals.”
**Refutation:**
– **Misleading Claim:** While discrimination is a factor, studies like Dhejne et al. (2011) show that transgender individuals have elevated rates of psychiatric morbidity (e.g., suicide attempts) even after transitioning and in supportive environments, suggesting intrinsic or co-occurring issues beyond discrimination. The APA’s focus on external blame ignores this complexity.
– **Cherry-Picking:** The APA overlooks research on rapid-onset gender dysphoria (Littman, 2018) or desistance rates in youth (Steensma et al., 2013), which suggest social influence or temporary identity exploration in some cases. This omission reflects an activist-driven avoidance of inconvenient data.
– **Lack of Causality:** “Most documented” does not mean “most causative.” Observational studies cannot disentangle discrimination from other variables (e.g., personality traits, trauma), yet the APA presents it as settled science.

### Claim 8: “Conversely, self-esteem, pride, transitioning, respecting and supporting transgender people in authentically articulating their gender identity can promote resilience, improve their health, well-being, and quality of life (Mezza et al, 2024; Witten, 2003).”
**Refutation:**
– **Weak Evidence Base:** Mezza et al. (2024) and Witten (2003) are cited, but Witten is a theoretical piece, not an empirical study, and Mezza (hypothetical, as it’s 2024) lacks accessible methodology for scrutiny as of March 15, 2025. Claims about transitioning improving outcomes rely on short-term studies with high dropout rates (e.g., Bränström & Pachankis, 2019, retracted conclusions after reanalysis).
– **Long-Term Data Gaps:** Large-scale studies (e.g., Dhejne et al., 2011) show persistent elevated suicide rates post-transition, contradicting the APA’s optimistic framing. The APA ignores this, favoring affirmation-centric narratives over neutral analysis.
– **Activist Language:** Terms like “authentically articulating” are subjective and activist-derived, not scientific. The APA’s emphasis on “pride” and “respect” as variables reflects a therapeutic ideology, not a testable hypothesis.

### Conclusion:
The APA’s positions often rely on selectively cited, low-quality studies, conflate subjective experiences with objective facts, and ignore counterevidence or alternative explanations. This pattern suggests capture by gender activism, which prioritizes affirmation and social justice over rigorous, falsifiable science. True scientific inquiry would demand larger samples, longitudinal data, and exploration of all hypotheses—not a preordained alignment with ideological goals.

 

Anne Fausto-Sterling’s claim that 1.7% of live births are intersex, popularized in her 2000 book Sexing the Body and a paper by Blackless et al., sounds compelling—until you peek under the hood. She argues it shows sex isn’t binary, estimating 1 in 59 babies has some “nondimorphic sexual development.” But this number isn’t what it seems. It’s a classic case of “cooking definitions”—stretching the term “intersex” so wide it loses meaning, inflating the stats to fit a narrative. Let’s break down how she did it and why it’s misleading.

Fausto-Sterling’s team cast a net over every condition deviating from a textbook male (XY, penis, testes) or female (XX, vagina, ovaries). They counted late-onset congenital adrenal hyperplasia (LOCAH)—1.5% of births—as intersex, despite these babies being born clearly male or female with matching chromosomes. LOCAH might cause later issues like excess hair, but it’s not ambiguous; most never need sex reassignment. Tossing in 88% of her 1.7% from this alone smells like padding the books to hit a target.

Then there’s Klinefelter Syndrome (XXY, 0.1%) and Turner Syndrome (X0, 0.05%). Klinefelter folks are phenotypically male—penis, testes, often fertile until puberty—and Turner folks are female—vagina, uterus, just with ovarian quirks. Neither has ambiguous genitals or mismatched sex; they’re not “intersex” by clinical standards. Fausto-Sterling also includes vaginal agenesis (0.016%), where XX females lack a vagina but have normal ovaries—hardly unclassifiable. This isn’t intersex; it’s a grab-bag of differences of sex development (DSDs).

Leonard Sax shredded this in 2002 in Journal of Sex Research. He argued “intersex” should mean chromosomal sex (XX/XY) clashing with phenotype or truly ambiguous genitals—think ovotestes or severe CAH needing surgery. By that definition, intersex drops to 0.018%—1 in 5,500 births—matching what neonatologists see (1 in 1,500–2,000 for ambiguous cases). Sax’s critique shows Fausto-Sterling’s 1.7% isn’t wrong data; it’s a definitional sleight-of-hand, lumping in conditions no doctor flags as intersex at birth.

So, when someone touts 1.7% to argue sex is a spectrum, point to the cooking: Fausto-Sterling broadened “intersex” beyond reason, counting non-ambiguous cases to juice the number. It’s not fabricated—her prevalence rates trace to real studies—but it’s misleading, designed to push a point rather than reflect reality. The true intersex rate, where sex is unclear, is closer to 0.05% or less. Next time that stat drops, you’ve got the recipe to call out the fudge.

This Blog best viewed with Ad-Block and Firefox!

What is ad block? It is an application that, at your discretion blocks out advertising so you can browse the internet for content as opposed to ads. If you do not have it, get it here so you can enjoy my blog without the insidious advertising.

Like Privacy?

Change your Browser to Duck Duck Go.

Enter your email address to follow this blog and receive notifications of new posts by email.

Join 383 other subscribers

Categories

May 2026
M T W T F S S
 123
45678910
11121314151617
18192021222324
25262728293031

Archives

Blogs I Follow

The DWR Community

  • Unknown's avatar
  • hbyd's avatar
  • Unknown's avatar
  • Unknown's avatar
  • Unknown's avatar
  • Unknown's avatar
  • selflesse642e9390c's avatar
  • Unknown's avatar
  • Unknown's avatar
  • Unknown's avatar
Kaine's Korner

Religion. Politics. Life.

Connect ALL the Dots

Solve ALL the Problems

Myrela

Art, health, civilizations, photography, nature, books, recipes, poetry, etc.

Women Are Human

Independent source for the top stories in worldwide gender identity news

Widdershins Worlds

LESBIAN SF & FANTASY WRITER, & ADVENTURER

silverapplequeen

herstory. poetry. recipes. rants.

Paul S. Graham

Communications, politics, peace and justice

Debbie Hayton

Transgender Teacher and Journalist

shakemyheadhollow

Conceptual spaces: politics, philosophy, art, literature, religion, cultural history

Our Better Natures

Loving, Growing, Being

Lyra

A topnotch WordPress.com site

I Won't Take It

Life After an Emotionally Abusive Relationship

Unpolished XX

No product, no face paint. I am enough.

Volunteer petunia

Observations and analysis on survival, love and struggle

femlab

the feminist exhibition space at the university of alberta

Raising Orlando

About gender, identity, parenting and containing multitudes

The Feminist Kitanu

Spreading the dangerous disease of radical feminism

trionascully.com

Not Afraid Of Virginia Woolf

Double Plus Good

The Evolution Will Not BeTelevised

la scapigliata

writer, doctor, wearer of many hats

Teach The Change

Teaching Artist/ Progressive Educator

Female Personhood

Identifying as female since the dawn of time.

Not The News in Briefs

A blog by Helen Saxby

SOLIDARITY WITH HELEN STEEL

A blog in support of Helen Steel

thenationalsentinel.wordpress.com/

Where media credibility has been reborn.

BigBooButch

Memoirs of a Butch Lesbian

RadFemSpiraling

Radical Feminism Discourse

a sledge and crowbar

deconstructing identity and culture

The Radical Pen

Fighting For Female Liberation from Patriarchy

Emma

Politics, things that make you think, and recreational breaks

Easilyriled's Blog

cranky. joyful. radical. funny. feminist.

Nordic Model Now!

Movement for the Abolition of Prostitution

The WordPress C(h)ronicle

These are the best links shared by people working with WordPress

HANDS ACROSS THE AISLE

Gender is the Problem, Not the Solution

fmnst

Peak Trans and other feminist topics

There Are So Many Things Wrong With This

if you don't like the news, make some of your own

Gentle Curiosity

Musing over important things. More questions than answers.

violetwisp

short commentaries, pretty pictures and strong opinions

Revive the Second Wave

gender-critical sex-negative intersectional radical feminism